Tag: Cell Biology
Showing all 2 results
-
Lipid Bilayers: Structure and Interactions
Original price was: $259.00.$207.20Current price is: $207.20.Add to cartLipid bilayers represent the fundamental model system for biological membranes. In recent years, we have been presented with a wealth of important insights into the structural and functional abilities of lipid bilayers with real possibilities in understanding the complex and varied behaviour of biological membranes. This volume is intended to give the researcher presently in the field and those wishing to enter the field a comprehensive overview into the current state of the art of lipid bilayer research. Detailed reviews are given on such topics as, lipid bilayer structure and dynamics, hydration of lipid bilayers, the role and behaviour of lipid bilayers on fusion and rupture, interaction of lipid bilayers and monolayers with small organic molecules and other additives such as proteins and finally, on the production and characterization of highly aligned bilayers under biologically relevant conditions. The book, besides being a reference, could be used in a graduate level courses with special emphasis in model membrane systems and physical techniques characterization.
-
Membrane Transporters: Methods and Protocols
Original price was: $169.00.$135.20Current price is: $135.20.Add to cartMembrane transporters and channels play key roles in drug absorption and distribution, influence drug efficacy and toxicity, and are the target of about 30% of currently marketed drugs. In Membrane Transporters: Methods and Protocols, a panel of recognized basic and clinical investigators-many world-famous-describe their proven, cutting-edge methodologies for studying these important proteins. Treated in step-by-step detail, these techniques take advantage of all the latest developments in biomedical research, including pharmacogenomics, bioinformatics, and microarray technologies. The authors explain databases and tools for bioinformatics analysis, provide practical guidelines for microarray experiments and data analysis, and illustrate the use of small-angle X-ray scattering, nuclear magnetic resonance (NMR), and molecular modeling to study the structural biology of membrane transporters. Methods for exploring structure-function correlation, such as site-directed mutagenesis, immunocytochemistry, and confocal microscopy, are also described, along with several methods that may help in the development of novel therapeutics. Each technique contains hands-on instructions, many notes on avoiding the problems that one may encounter, and suggestions for variant procedures.
Comprehensive and highly practical, Membrane Transporters: Methods and Protocols offers investigators working in biopharmaceutical science, drug discovery, and drug delivery both an array of powerful tools for work on membrane transporters and an essential guide to the state-of-the-art in the membrane transporter field today.
